99% Apixaban CAS 503612-47-3

Kufotokozera Kwachidule:

Dzina la Chemical:Apixaban
Dzina lina:1-(4-Methoxyphenyl) -7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl) -4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine -3-carboxaMide;1-(4-Methoxyphenyl) -7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl] -4,
5-dihydropyrazolo[3,4-c]pyridine-3-carboxaMide
Nambala ya CAS:503612-47-3
Chiyero:99% mphindi
Fomula:C25H25N5O4
Kulemera kwa Molecular:459.50
Chemical Properties:Apixaban ndi ufa woyera wa crystalline.Ndi mtundu watsopano wa oral Xa factor inhibitor, ndipo dzina lake lamalonda ndi Eliquis.Apixaban amagwiritsidwa ntchito pochiza odwala akuluakulu omwe akuchitidwa opaleshoni yosankha m'chiuno kapena mawondo kuti ateteze venous thromboembolism (VTE).

Titumizireni imelo

Tsatanetsatane wa Zamalonda

Zolemba Zamalonda

Kufotokozera

ITEM	ZOYENERA
Maonekedwe	Yoyera mpaka yoyera yolimba
Chiyero	≥ 99%

Kugwiritsa ntchito

Apixaban ndi mtundu watsopano wa oral anticoagulant, mtundu watsopano wa oral factor Xa inhibitor, womwe umagwiritsidwa ntchito poletsa ndi kuchiza magazi.
Apixaban ndi oral factor Xa inhibitor yatsopano yopangidwa pamodzi ndi Bristol-Myers Squibb ndi Pfizer.Poletsa coagulation factor Xa, apixaban imalepheretsa kubadwa kwa thrombin ndi thrombosis.

Pa Epulo 26, 2007, Bristol-Myers Squibb ndi Pfizer adalengeza za chitukuko chatsopano cha oral anticoagulant apixaban ya Bristol-Myers Squibb ngati njira yopititsira patsogolo ya warfarin.
Mu May 2011, apixaban inali yoyamba kuvomerezedwa pofuna kupewa venous thrombosis kwa odwala akuluakulu omwe amachitidwa opaleshoni yosankha m'chiuno kapena mawondo m'mayiko a 27 EU, Iceland ndi Norway.
Pa November 20, 2012, European Commission inavomereza ELIQUIS (apixaban) pofuna kupewa matenda a stroke ndi systemic embolism mwa akuluakulu omwe ali ndi non-valvular atrial fibrillation (NVAF) omwe ali ndi chiopsezo chimodzi kapena zingapo.
Bungwe la Canadian Food and Drug Administration, Japan, ndi US Food and Drug Administration pambuyo pake linavomereza ELIQUIS (apixaban) pofuna kupewa sitiroko ndi systemic embolism mwa akuluakulu omwe ali ndi non-valvular atrial fibrillation (NVAF) omwe ali ndi chiopsezo chimodzi kapena zingapo.
Pa Epulo 12, 2013, ELIQUIS (Apixaban), idalengezedwa pamsika ku China.Apixaban ndi buku la oral factor Xa inhibitor pofuna kupewa venous thromboembolism (VTE) mwa odwala akuluakulu omwe akuchitidwa opaleshoni ya m'chiuno kapena mawondo.Kukhazikitsidwa kwake kumapereka njira yatsopano yotetezeka komanso yothandiza ya anticoagulation pambuyo pa opaleshoni ya mafupa m'machitidwe azachipatala, ndipo imabweretsa uthenga wabwino kwa odwala aku China omwe akusinthidwa m'chiuno / bondo.
Kafukufuku wazachipatala watsimikizira kuti poyerekeza ndi 40 mg subcutaneous jakisoni wa enoxaparin kamodzi patsiku, 2.5 mg ya ELIQUIS (Apixaban) pakamwa kawiri pa tsiku ndi yothandiza kwambiri popewa zochitika za venous thromboembolic pambuyo pa opaleshoni ya m'chiuno kapena mawondo, ndipo siziwonjezera chiopsezo cha kutuluka magazi.